The Effect of High Intensity Interval Training on Serum Levels of Aspartate Aminotransferase, Alanine Aminotransferase, Insulin Resistance, and Lipid Profile in Women With Fatty Liver
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Paper ID : 1588-12THCONG
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1M.Sc student of sport physiology, Shahid Madani University of Azerbaijan
2Assistant Professor of Sport Physiology, Shahid Madani University, Tabriz, Iran
Non-alcoholic fatty liver disease is a liver inflammation caused by excessive accumulation of fat in the liver tissue. It sometimes interferes with the normal functioning of liver tissue, including cirrhosis. Exercise and physical activity can potentially be effective in reducing liver fat. Intense interval exercises increase metabolism and maintain it at a high level for up to 24-48 hours after exercise, increasing insulin sensitivity in the muscle, increasing levels of growth hormones, and decreasing appetite after exercise. The aim of this study was to investigate the effect of intense interval training on serum levels of aspartate aminotransferase, alanine aminotransferase, insulin resistance and lipid profile in women with fatty liver.
The present study was a clinical trial with 28 women with non-alcoholic fatty liver disease. The exercise protocol was intense (eight weeks / three days / 60 minutes per session). Exercise intensity was also controlled using the Borg criterion. Assessment of variables was done 24 hours before and after the first and last training session. Blood count was measured by ELISA method. Data were analyzed by paired and independent t-test at the significant level (p <0.05).
The results showed that after eight weeks of intense interval training, HDL significantly increased and aspartate amino transferase, alanine amino transferase, LDL and triglyceride significantly decreased and But insulin resistance was not significantly reduced.
Considering the significant effect of severe interval exercises on women with non-alcoholic fatty liver disease, it can be concluded that these exercises can improve the severity of the disease in these patients.