Investigation the effect of Alpha Lipoic Acid (ALA) supplementation on exercise: a review article
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Authors
1Undergraduate Student of Occupational Therapy, Faculty of Science and Rehabilitation, Iran University of Medical Sciences, Tehran, Iran
2Master of Health Sciences in Nutrition, Tehran University of Medical Sciences, School of Nutrition and Dietetics, Tehran, Iran
3MSc, Exercise Physiology, Department of Physical Education and Sport Sciences, Science and Research Branch, Islamic Azad University, Tehran, Iran
Abstract
Flavonoids are phytonutrients associated with the varied colors found in fruits and vegetables. Alpha Lipoic Acid (ALA), also called Thioctic Acid is one of the Flavonoids(antioxidant) that possibly effective for atherosclerosis, cardiovascular disease, hypertension, and pneumonia and often used to treat neuropathy. Also ALA supplementation resulted in a protection against oxidative stress caused by exhaustive exercise.Therefore, the purpose of this article is to investigate the effect of ALA supplementation on exercise.
This study is a review article using different sources on the use and role of alpha lipoic supplement on sport performance through library and internet searches and using keywords such as Alpha Lipoic Acid, ALA supplement and their role on exercise in Persian and English at PubMed, SID, Science Direct, Medline, Scopous and Iranmedex.
The most important role of ALA in the body is in the fight against the effects of free radicals. ALA is very important for digestion, absorption and energy production. Also, it helps enzymes convert nutrients into energy and helps in supplying creatine, carbohydrates and other essential nutrients to the muscle tissue needed to increase strength and endurance as well as muscle tissue. ALA resists in preventing or repairing muscle damage in both endurance and resistance exercise. Endurance athletes pump greater amounts of oxygen through their respiratory system during exercise than at rest. It also pumps a lot of oxygen to burn glucose and further oxidize damage by free radicals during exercise where ALA comes in to neutralize these free radicals. In addition, ALA increases creatine uptake.
ALA participates in cellular metabolism in mitochondria for energy production. For an athlete, endurance requires constant energy. On other hands, ALA can increase training time and improve muscle strength. In general, ALA helps prevent muscle damage caused by free radicals during exercise and improves muscle recovery. The result of the many health benefits of ALA has made it a popular supplement among endurance and endurance athletes. But there are few human studies of the effect of ALA on exercise.
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