Reduction Techniques of Graphene Oxide for Application in Bone Tissue Engineering Scaffolds Due to Sports Injuries

Poster Presentation
Paper ID : 1162-12THCONG
Oral / Poster Presentation File: همایش ورزشی.jpg 
1Master’s degree in medicine engineering (Biomaterial), School of Advanced Technologies in Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
2Assistant professor, Department of Physiology, Faculty of Center of Physical Education, Isfahan University of Technology
3Bachelor Student, Department of Materials Engineering, Isfahan University of Technology
Bone injuries are one of the most common injuries among athletes, due to their high speed while running, there is a lot of pressure and force applied to the body; it has made athletes susceptible to bony injuries. Treatment of bone disorders with tissue engineering is one of the new therapeutic methods. The design of three-dimensional tissue engineering scaffolds, with appropriate physical and mechanical properties, is crucial for faster bone regeneration. The use of ceramics is one of the effective compounds in optimizing the mechanical properties of the scaffold. Graphene derivatives are from the bioactive ceramics that are highly efficient in tissue engineering. Graphene oxide is a two-dimensional monolayer material, with hexagonal crystalline lattice and sp2 hybridization with a high number of oxygen-active groups on the surface. The presence of reactive oxygen groups on the surface results in the structural defects and severe decrease in the mechanical, thermal and electrical properties of this carbon nanostructure. In an effort to produce materials with higher mechanical, thermal and electrical properties, extensive research has been undertaken to reduce GO. Reduction reaction eliminates oxygen groups, increases surface charge and facilitates charge transferring to maintain solubility and colloidal stability, and improves the physical and chemical properties of graphene oxide. The aim of this study was to review the processes of graphene oxide depletion for bone tissue engineering.
The study was a review. On reputable scientific related websites or tissue engineering journals and clinical sciences and mainly: Science Direct, PubMed, Springer, Google Scholar, etc. From 2005 to 2019 by searching for keywords Bone Tissue engineering, reduce Graphene Oxide, Sport, and etc. done. 30 articles reviewed.
The results of previous literature review indicate that the reduction process can be thermal (using above 1900 ° C), chemical (reducing agent in low temperature) or electrochemical (electron exchange between GO and electrodes) each of which leads to Differences in morphology, electrical properties and so on.
Discussion. The results of previous studies showed that the best method is chemical regeneration with the help of green regenerative factors with regard to human health and the environment.