Comparison of effects of high and moderate intensity intermittent exercises on plasma levels of orexin-A, glucose, insulin and insulin resistance in overweight and obese women

Poster Presentation XML
Paper ID : 1044-12THCONG
Oral / Poster Presentation File: کد مقاله 1044.jpg 
Authors
1Sport Physiology, Sport Sciences, Isfahan University, Isfahan, Iran
2Sport Physiology, Sport Sciences, University of Isfahan, Isfahan, Iran
Abstract
Orexin is neuropeptide with wide functions in the central nervous system and plays an important role in energy balance and obesity. The aim of this study was to compare the effects of high and moderate intensity intermittent exercises on plasma levels of orexin-A, glucose, insulin and insulin resistance index in overweight and obese women.
29 obese and overweight women 25-45 years were voluntarily selected and optionally assigned into three groups: HIIT: (BMI=29.43±3.16 (kg. m2), n=11), MIIT: (BMI=27.63±2.82 (kg. m2), n= 9), and control (BMI= 28.77±4.28 (kg. m2), n= 9). The experimental groups performed a training protocol up to 3 sessions per week for 8 weeks with an intensity of 90-75% for the high intensity group and an intensity of 65% -80% of the heart rate for the moderate intensity group. Data analysis was conducted by ANCOVA test, (p≤0. 05).
The results indicated an increase in plasma levels of orexin (HIIT= %17. 14, MIIT= %12. 02) and a decrease in amounts of glucose (HIIT= %1. 61, MIIT= % 3.02), insulin (HIIT= % 38.35, MIIT= %10. 26), insulin resistance index (HOMA-IR) (HIIT= %37. 68, MIIT= %15. 50), uric acid levels (HIIT= %1. 28, MIIT= %3. 85) and body fat percent (HIIT= %7. 23, MIIT= %4. 46) of experimental groups compared to control group, but these changes were not statistically significant (P≥0. 05). Only a significant (meaningful) increase in the cardiorespiratory endurance of subjects (HIIT= %15. 27, MIIT= %10. 46) was shown in the two training groups compared to the control group (P≤0. 05).
In general, it seems that 8 weeks of interval trainings with different intensities increased orexin levels and improved some of the elements linked with obesity. Although there were no significant differences between the two exercises, training protocols, but this change in the high intensity group was higher than the moderate intensity group.
Keywords
Subjects